Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical microinfarcts

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Cerebral Hypoperfusion Generates Cortical Watershed Microinfarcts in Alzheimer Cerebral Hypoperfusion Generates Cortical Watershed Microinfarcts in Alzheimer Disease

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Cerebral hypoperfusion generates cortical watershed microinfarcts in Alzheimer disease.

BACKGROUND AND PURPOSE The watershed cortical areas are the first to be deprived of sufficient blood flow in the event of cerebral hypoperfusion and will be the sites of watershed microinfarcts. Cerebral hypoperfusion is associated with Alzheimer disease (AD), but information regarding the occurrence of watershed cortical infarcts in AD is lacking. METHODS Brains of 184 autopsy cases (105 def...

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Cerebral amyloid angiopathy.

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Cerebral amyloid angiopathy.

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ژورنال

عنوان ژورنال: Acta Neuropathologica

سال: 2011

ISSN: 0001-6322,1432-0533

DOI: 10.1007/s00401-011-0925-9